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empty-ego OP t1_jec4duj wrote


>Objective: Major depressive disorder (MDD) has a relapse rate that cannot be ignored and places a tremendous burden on the patient in the prevention and treatment process. Yoga, a combination of physical and mental exercises, is effective and acceptable for the adjunctive treatment of MDD. This study aimed to explore further the evidence of yoga’s efficacy for patients with MDD.
>Methods: PubMed, Embase, Cochrane library, PsycINFO, SinoMed, CNKI, Wanfang, and VIP databases from their inception to 13 October 2022 were searched by a pre-defined search strategy. RCTs of patients with MDD who met diagnostic criteria for yoga treatment were included. RoB2.0 was used to evaluate the quality of the literature. Improvement in depressive symptoms was assessed by the Beck Depression Inventory (BDI), Hamilton Depression Rating Scale (HAMD), or other scales were used as primary outcome indicators, and improvement in anxiety was assessed by the Hamilton Anxiety Scale (HAMA) and State–Trait Anxiety Inventory (STAI) scale as secondary outcome indicators. RR and Cohen’s d at 95% CI were used as effect size estimates, and Q and I2 were used to evaluate the size of heterogeneity, with a p-value less than 0.05 indicating statistical significance.
>Results: Thirty-four RCT studies, including 1,269 patients in the treatment group and 1,072 patients in the control group, 48.4% of whom were women, were included in the study. Compared to the control group, the BDI-II results yielded a moderate effect of yoga on the improvement of depressive symptoms (Cohen’s d = −0.60; 95% CI: −1.00 to −0.21; p < 0.01), the HAMD results yielded a moderate improvement of yoga on the severity of depressive symptoms (Cohen’s d = −0.64; 95% CI: −0.98 to −0.30; p < 0.01), and the STAI results can be concluded that yoga had a negligible effect on the improvement of the level of anxiety (Cohen’s d = −0.26; 95% CI: −0.48 to −0.04; p = 0.02). No adverse events occurred in the yoga group during the treatment.
>Conclusion: Yoga can improve depressive symptoms and anxiety in patients with MDD and has a safe and wide patient acceptance.


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Brain_Hawk t1_jechvp1 wrote

Ok so first. Frontiers is trash..I'm embarrassed I ever published therein. Also what does it mean "improvement of symptoms but also their severity"? How is improving symptoms not the same as improving their severity, or am I misreading that?

And the language in that abstract. Wow. Relapse rate that cannot be ignored indeed. I suspect a non native speaker, for which I feel so much empathy ( so hard, imagine doing it in a.sdcond language!!) But that passed review and editors. Very non scientific language in the abstract.

Results ok maybe interesting. Bigger question toe is how it compares to other interventions (I'll admit didn't read that much!) To.some extent, doing nearly anything might improve depression. Sonia yoga better than, say, joining a lawn bowling league? Is it the yoga or the social, etc aspect.

Though one hopes many such studies on yoga had appropriate active controls so mayne im guilry of that thing where people dismiss research via a false belief the researchers lacked basic competence.

I should quick read it but I'm in a Lyft and.almost home, the science day is done :)


ghsgjgfngngf t1_jeemyv1 wrote

I'm sure that the effect is real and also that it would probably be comparable to many other interventions that are activities (and not something like handing them a leaflet). It's exercise and of course exercise has a positive effect.


Sparkysparkysparks t1_jeds8ur wrote

Yeah - I had a good look at the inclusion criteria and the table of included studies. Lots of them did not have any kind of active control eg waitlist control or none). Therefore we don't really know if yoga is better for these symptoms than just reading a book or stretching or going for a run - or even just doing something new (Hawthorne effect).


MadcapHaskap t1_jeekcs0 wrote

As a good generalisation, I don't take sociological studies seriously unless they figure out how to double blind it. Otherwise the effect inevitably hoes away when researchers with the opposite bias try it.


Brain_Hawk t1_jeeqlqc wrote

This isn't sociological. It's interventional psychiatry.

Some things of course cannot be blinded, because well it's an intervention that people know they got. And it will design study you can compare the efficacy of different interventions.


MadcapHaskap t1_jeetcd8 wrote

Blinding things can be tough, sure.

But the efficacity is inevitably what the researchers think it should be. Get some researchers with a negative opinion of yoga, and you'll get negative outcomes.


futureshocked2050 t1_jecy3z8 wrote

Next we'll learn that the polyvagal system almost directly correlates to Chakras and that the polyvagal system can be directly manipulated for positive health results.