You must log in or register to comment.

NeosPhilopator OP t1_jees1i6 wrote

> Publicly available summary-level GWAS data on SUA were obtained from a genome-wide meta-analysis (N = 121,745) based on three Japanese cohorts, including the Japan Multi-institutional Collaborative Cohort (N = 10,621), the Kita-Nagoya Genomic Epidemiology (N = 2,095), and the Biobank Japan (N = 109,029)

> We found a potential causal association between higher SUA levels and increased prostate cancer risk. The findings were robust when different MR methods (MR Egger, weighted median, and weighted mode) were used.

> There are some potential mechanisms for the positive association between SUA and prostate cancer risk. [...] SUA may play a role in cancer biology by inducing chronic inflammation. [...] Although SUA may exert as an antioxidant by scavenging reactive oxygen species (ROS), the antioxidant property may be harmful.


AutoModerator t1_jeer7r6 wrote

Welcome to r/science! This is a heavily moderated subreddit in order to keep the discussion on science. However, we recognize that many people want to discuss how they feel the research relates to their own personal lives, so to give people a space to do that, personal anecdotes are allowed as responses to this comment. Any anecdotal comments elsewhere in the discussion will be removed and our normal comment rules apply to all other comments.

I am a bot, and this action was performed automatically. Please contact the moderators of this subreddit if you have any questions or concerns.