Technical_Sir_9588 t1_jc1xrfi wrote
Reply to comment by snappedscissors in New information about the role of a molecule found in chillis in reducing foot pain by healing damaged nerves. After three months, the team found that those who’d been treated with the capsaicin patch reported that their pain had reduced significantly, compared to those treated with standard care by Wagamaga
What I understand from some other research is that when these peripheral nerves become sensitized they spontaneous sends afferent signaling to the spinal cord - > brain without any external stimuli. This sustained signaling drives central sensitization. The idea is that central nervous system plasticity allows the reversal from central sensitization to the norm if these external stimuli reinforcing the [pain/damage/harm] are removed, especially since no actual sustained damage to the tissues is present.
I also educate my patients on the benefits of prolonged fasting, with the potential "repair" of peripheral nerves, spinal cord, etc. via autophagy. There is definitely research out there using mouse subjects and I wish more research funds would go towards this end but fasting isn't sexy more is its profitable.
The combo of fasting and capsaicin seem to provide the best outcomes.
[deleted] t1_jc97fbu wrote
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