unswsydney OP t1_jc5iic1 wrote on March 14, 2023 at 4:38 AM

Afternoon r/science! A team of UNSW and Garvan Institute researchers have found that introducing bacteria to a tumour’s microenvironment creates a state of acute inflammation that triggers the immune system’s primary responder cells to attack rather than protect a tumour.

The research could lead to better treatments to improve outcomes for people with advanced or previously untreatable cancers.

The work has been published in the journal Cancer Research, and is available to read here: https://aacrjournals.org/cancerres/article/doi/10.1158/0008-5472.CAN-21-4025/716558/Neutrophil-conversion-to-a-tumor-killing-phenotype

IllustriousLP t1_jc7cvb9 wrote on March 14, 2023 at 4:05 PM

Thanks for posting. I have a rare cancer called sarcoma , makes me want to ask my oncologist about this. I am on keytruda and this immunotherapy drug is very effective. Destroying all the tumors that recently formed in my lungs.