This is not novel at all, and not feasible from an oncology perspective. PD-L1 and CTLA4 are badass drugs with awesome immune mediation with limited other effects. Let's support what we have, instead of coming up with ridiculous ideas. There is not enough data about this class of drugs, and it NEEDS to be researched because it's possible that immunotherapy is cheaper and more effective than chemotherapy but unfortunately it's only studied in late stage/refractory cancers or tried in melanoma where immunoglobulins are known to be effective. Anyway, let's research what matters and not this stupid BS.