Anthrogal11 t1_is7myux wrote on October 13, 2022 at 9:56 PM

Reply to comment by ZSpectre in SARS-CoV2 enters the brain through the olfactory nerve in rhesus monkeys, causing neuroinflammation. The virus spread further into the brain in aging animals. by andyhfell

Thanks! I’m super curious both as an academic and because I have pretty awful allergic rhinitis all year (I know, the jokes write themselves). I’m triple vaxxed but I had just graduated at beginning of pandemic and worked in a service capacity throughout. My son got it and we live in close quarters. There was no isolation. I’ve managed to not catch it (so far). I’m so curious if the curse of severe allergies has potentially provided a benefit in terms of avoiding Covid. Thanks for your response and insights!

sgnirtStrings t1_is85na2 wrote on October 14, 2022 at 12:15 AM

I'm 4x original vax and 1 new bivalent vax. Never gotten it before. Also a sufferer of severe allergies and allergic rhinitis for >10 years. That's my random data point.

Random aside: I've been doing allergy shot immunotherapy for ~4 months and holy hell it works. My shallow research into a couple papers reveal a theory of how it might work: I'm simply exhausting the differentiated immune cells that I have for each specific allergen. And then after a certain length of time being consistently exposed, the cells start going "whoops I guess I give up, time to die". And that's possibly why allergic immunotherapy can cure people's allergies.

Just mentioning that because I wish someone told me about the treatment 10 years ago! Used to take 1-2 antihistamines a day. Now I take none. (And I'm talking allergies to 40+ different pollens in the area).

Anthrogal11 t1_is9si16 wrote on October 14, 2022 at 10:29 AM

Thanks! I have talked to my allergist about this because I’m on prescription antihistamines twice a day. I’ll talk to them further. I appreciate your insights!