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gauchocartero t1_isah59s wrote

Look at some of the proteins upregulated in the chart: YAP1, ITGB1, VASP, EZR, EGFR, RHOQ, NFKB, CDK2… All of these proteins are associated with increased tension in the cellular microenvironment as a result of abnormal matrix deposition, inflammation, oxidative stress.