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[deleted] t1_isjq5d1 wrote



Fun_Wind7710 t1_isjvti5 wrote

It sounds mainly like "your body prefers to burn ketones over glucose", but I'm also a crayon eater


NewSinner_2021 t1_isk2qz4 wrote

Stop being greedy and pass the the color grey. It's my favorite.


AndyGHK t1_iskuk8i wrote

Regrettably (as far as I understand) this is true for all except the brain, which loves glucose so much that, even when in ketosis, it will tell the body to break down proteins and muscles to get glucose to function.


BafangFan t1_isk4crg wrote

Increasing your body's ketone levels [helps avoid] the turning-on of new-fat-making hormones, and also helps avoid the condition of insulin resistance.


reshef t1_iskd003 wrote

Translating from just the title: “putting ketones into your body prevents new fat from being made and prevents insulin resistance from being built” which is interesting because it means that it isn’t necessarily the breakdown OF fat that prevents new fat from being made, but merely the presence of the resulting ketones.


[deleted] t1_islgqwu wrote



reshef t1_islh7ok wrote

Well that’s the thing, they don’t, but apparently they do prevent you from forming new fat or becoming insulin resistant


ptahonas t1_isl4po8 wrote

Ah yes, another nice non biased article from "Meatrition"


lucid1nt3rval t1_islgs61 wrote

This is a very complex methodology, but here's what I understood from this paper.

They enrolled 8 healthy males between 22-35 years of age with a normal BMI.

Gave everyone a Growth Hormone infusion.

Then one-half of the subjects got Ketones (betaOHB) and the other half got saline (control group) as an intravenous infusion. There were 2 visits a month apart and each person got a chance to be in each group (that's the crossover design).

Growth Hormone increases Free Fatty Acids (FFA) in your body by breaking down fat (lipolysis), but if a participant was in the Ketone infusion group, their serum FFA became markedly lower during betaOHB (Ketone) infusion even after getting the Growth Hormone. The study found that Ketones block the breakdown of fat through binding to HCA2 receptor.

During the betaOHB infusion, lots of Ketones entered the skeletal muscle tissue and promoted glucose uptake, which increases insulin sensitivity in the skeletal muscle. Also the betaOHB that entered the skeletal muscle was immediately converted to Acetoacetate and entered Krebs Cycle.

Bottomline: Having extra ketones promotes uptake of glucose by muscle, which lowers your blood glucose level and improves your insulin sensitivity.


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