My uncle and a cousin both developed schizophrenia when they hit puberty. My uncle killed himself, while my cousin tried to kill his sisters when he was 14 with a knife so has been away since...he's now 64. Their lives were very stressful. Lots of neglect and abuse by their fathers. My uncle went into the Navy and was severely hazed. After he came out of the service he wasn't the same. Lasted into his 30s. He used to see witches. My grandmother was the worst mother to him and my grandpa was a WWII vet who once told my mother while she was on her period that she could only use two pieces of toilet paper. The stress from their lives definitely pushed them into it. Also of note, they both have celiac disease which is massively inflammatory. My grand mother is in her 90s, still mean as hell, and they have her on psych meds for bipolar/schizophrenia (they're used for both). It took her until her 80s for anyone to do anything about it. It doesn't really help her behavior though.