Submitted by HurpDurp54 t3_y8dnho in science
Comments
blacksmithjohnson t1_iszsp5s wrote
Explain like I'm 17 and have middling intelligence please.
HurpDurp54 OP t1_iszv7ta wrote
Chromatin unravels at a particular gene involved with anxiety, leaving it susceptible to protein-gene interaction (change in dna) and priming the brain for continued alcohol use and dependence.
curious_geoff t1_it04soy wrote
What about huge doses of alcohol every day?
[deleted] t1_it06liz wrote
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binz17 t1_it078mn wrote
'role in epigenetics' means that this effect is observed even in mature people? or is it still limited to fetuses?
HurpDurp54 OP t1_it0auyq wrote
Epigenetics is when the environment, or in this case, behavior and consumption of alcohol can change DNA expression. In itself, it does not affect gametes, it is simply a change in expression (it becomes available to transcription proteins). Part of the discussion describes how some people may be more suceptible to these DNA expression changes, and may explain hereditary addiction. Possibly it is a mechanism to keep the brain in homeostasis.
HurpDurp54 OP t1_it0b5v8 wrote
I believe they did a trial with that as well, you'll have to search through the paper.
whiffling_waterfowl t1_it0geih wrote
susceptible (so sorry)
whiffling_waterfowl t1_it0h369 wrote
Drinking even a little bit of alcohol can alter your gene expression (epigenetics) and make you more likely to develop Alcohol Use Disorder (aka alcoholism). This may affect people with anxiety more than others.
[deleted] t1_it0hycc wrote
admcfajn t1_it0hzyh wrote
> sucestipal
That typo is so epic it's almost not worth correcting. Literally how I would mis-pronounce the word.
whiffling_waterfowl t1_it0iabj wrote
Ha yeah, I figured it was so off that even auto correct didn't have a clue.
Druid___ t1_it0ogob wrote
That makes you even more addicted. I conducted my own research. ;)
[deleted] t1_it0t0fe wrote
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WeirdNMDA t1_it0tvw0 wrote
Phenotype = genotype (your genes) + environment (your life, diet, behavior, habits, etc)
Epigenetics is about the expression of your genes, i.e. chages that can occur without having a DNA change.
[deleted] t1_it0twmk wrote
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flightwatcher45 t1_it10bun wrote
Guess what large quantities do!
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