Viewing a single comment thread. View all comments

Predawnbread t1_iyc1tyw wrote

28% improvement in cognitive decline and the risk of hemorrhages and swelling doesn't seem worth it ??? Like would you even be able to notice such an improvement? Seems a lil risky for basically no benefit I hope it doesn't get approved


sprouting_broccoli t1_iyc7vg1 wrote

The important bit is that targeting amyloid removal appears to have reduced the decline in patients which offers a way forward for other treatment options. Unfortunately this doesn’t seem like the right one but it’s likely this research will lead to much better alternatives going forward.


TreesAreNiceThings2 t1_iyc8hqb wrote

Be patient, these trials are expensive and how to best use these drugs remains up for debate.

This is a breakthrough for more reasons than just “we have a pill ready”. Its an important proof of concept and step forward in developing therapeutic strategies. We have learned a ton from trials the last 2 decades.


CityWizard t1_iyc9f2c wrote

It's too risky, 28% is insignificant for the risk and cost of the drug. You're looking at a $20-30K USD/year and 17% chance for brain hemorrhage.


Predawnbread t1_iyc22g0 wrote

Will be v costly to prescribe too as monitoring is needed and drug infusion times


Katana_sized_banana t1_iydcfkj wrote

I don't know but for some people 28% of the total can be the difference between stupid and vegetable.


sockalicious t1_iycxvyy wrote

People receive therapies for incurable cancers that have far worse side effects. AD is an incurable, terminal disease and some folks would be able to use the extra time this treatment provides.