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Can someone dumb this down for me

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Your retina tries to deal with high blood sugars (diabetes) when its mitochondria activate an internal recycling process called autophagy (which means “to eat oneself”). Essentially the mitochondria must sense the damage of primarily proteins and breaking these damaged proteins down and rebuilding is undertaken.

This is unlike my son’s room … when clothes and various other junk build up .. no internal cleaning mechanisms are activated (no junk-ophagy) until my wife yells a lot.

https://www.reddit.com/r/science/comments/z80uyr/hyperglycemia_promotes_mitophagy_and_thereby/iyakit0/?utm_source=share&utm_medium=ios_app&utm_name=iossmf&context=3

How’s that ?

I read through the study a couple times and still not exactly clear on the conclusions. It appears to say the study showed less damage as time went on as your body learns to deal with High BG more effectively, but in real world scenarios there is more damage in the long run.

Well yeah , it simply mitigates. It's not as healthy as normal levels

so occasional overeating can be beneficial?