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Phoenix042 t1_j1ebw5d wrote

But pain itself is a perception...

Altering that perception is the important part of treating pain. Blocking pain receptors is irrelevant in comparison.

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Fit-Anything8352 t1_j1flrae wrote

If you can will yourself to perceive less pain independent of the drug then you don't need the drug. Substitute a sugar pill and convince yourself to feel less pain the same way. That's what the placebo effect is.

If you were developing a new pain medication and in a clinical study you found that 50% of the control group felt less pain and 50% of the group who took your drug felt less pain, you would classify your drug as ineffective, because it doesn't do anything. Not as 50% effective because everyone felt less pain.

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