Comments
agwaragh t1_j093teb wrote
These days they'll likely charge an additional monthly subscription fee for that info.
cdotterhamilton t1_j09vg5r wrote
It’s worth it. I found out that my cluster of ailments were actually undiagnosed Hashimoto’s Disease. I have the genes related to increase in risk of development.
It has saved my life. I had multiple suicide attempts until they found those genes and were able to treat the hypothyroidism. It effected everything in my life and doctors didn’t take any of my complaints as being related.
Froobyflake t1_j0aacv5 wrote
That's because doctors aren't geniuses like everyone pretends. Half of them are mediocre at what they do, especially with mental health specialists
GoochMasterFlash t1_j0bpfcy wrote
I dont think it even has to do with intelligence necessarily. The vast majority of people want their job to be easy to do. The same way that someone running a restaurant doesnt want to deal with a picky customer, the same way that a mechanic wants to work on a nice car with a few easily identifiable problems, etc.. Doctors also just want peoples issues to be quick and easy for them. Most dont like dealing with complicated people who they dont know how to help quickly. Often they will make a quick fix solution to your problems even when it does nothing to help you holistically and can make other things worse.
Ive seen a lot of doctors and the vast majority strike me as people who went into it for the money. There are a few genuinely good doctors who want to help people first and foremost but a ton of them just want easy patients and a nice paycheck
Icarus367 t1_j0d5c54 wrote
Half are below average...
draeath t1_j0bsdkg wrote
It'll have to go on a new chip revision and samples reanalyzed, unless they're already grabbing these genes for another reason.
Wagamaga OP t1_j085q3f wrote
A large study of military members led by researchers at Duke Health and the Durham VA identified four genes that are linked to an increased risk of suicidal thoughts and behaviors.
While more work is needed to determine whether identification of the genetic markers might lead to targeted treatments, the findings advance the understanding of how inherited risk factors play a role in the pathology of suicidal thoughts and actions.
“It’s important to note that these genes do not predestine anyone to problems, but it’s also important to understand that there could be heightened risks, particularly when combined with life events,” said Nathan Kimbrel, Ph.D., associate professor in the Department of Psychiatry & Behavioral Sciences at Duke and co-lead author of the study publishing online Dec. 14 in the journal JAMA Psychiatry.
Kimbrel and colleagues, including co-lead author Allison Ashley-Koch, professor in the Department of Medicine at Duke, conducted a large, diverse, genome-wide analysis using data from 633,778 U.S. military veterans. Of the participants, 71.4% were of European ancestry; 19.1% African ancestry; 8.1% Hispanic; 1.3% Asian. Study participants were primarily male, with 9% female.
Within that group of veterans, 121,211 cases of suicidal thoughts or actions were identified from medical records. Participants were classified as controls if they had no documented lifetime history of self-harm behaviors.
https://jamanetwork.com/journals/jamapsychiatry/article-abstract/2799487
noahspurrier t1_j09ishh wrote
I wonder if the gene testing services like 23 And Me test for this.
cdotterhamilton t1_j09vocr wrote
Eventually, I have no doubt. But it is an added charge but is updated frequently as the research comes back and is peer reviewed.
draeath t1_j0bsjhg wrote
Keep in mind they use a chip for sample analysis. If they're not already capturing these genes, they either need a new chip revision and have to rerun samples, or they have to rely on studies finding an association with things they already know about you.
(You can opt into sample storage for future work, but it's been years and they haven't created a new chip revision yet)
thecowintheroom t1_j0bpvae wrote
Hispanic non European it’s a hundred sided die. If you’re Asian it’s a fifty sided die . If your African it’s a five sided die. If you’re white it’s a die where seven out of ten sides of the decagon give you suicidal impulses.
But only out of these, for ease, 700,000 people, did this phenomena occur. With a different data set maybe some other pattern would come up which could further the research. But it would probably use the same genome set. I mean how many copies of various human genomes can exist. How many exist? Does anyone know?
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[deleted] t1_j08mb0s wrote
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[deleted] t1_j0ba6ev wrote
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Icarus367 t1_j0d5wxs wrote
Until the next paper which fails to replicate the findings, which seems to be par for the course with these types of studies.
skkkkkt t1_j08cfus wrote
It’s like multicellular apoptosis, more or less necrosis
lifemanualplease t1_j088hgq wrote
I hope 23andMe includes this in all their testing