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AlbinoWino11 t1_j0dca54 wrote

Reply to comment by elixirsatelier in Concentrations of psychoactive compounds in mushrooms are extremely variable by mightx

I guess I struggle to see how this could be done with wild harvested mushrooms in a meaningful way. Perhaps with cultivated mushrooms. But then we won’t really know if the results are relevant to real world situations.

Have you considered contacting the authors with feedback?

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pseudocultist t1_j0e2dod wrote

I don’t know anyone who has taken wild grown psychedelics since the 70s. It’s all cultivated these days. It’s dangerous to take wild mushrooms and thankfully we have gotten that point across.

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AlbinoWino11 t1_j0e4aqk wrote

Heaps of folks near me (Australasia) hunt wild Psilocybe. I help moderate several specialist groups focused on ID and harm reduction so do get to see quite a lot of activity. Although US and some EU countries loosening restrictions definitely has skewed things towards cultivation.

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pseudocultist t1_j0f5ctt wrote

Ahh yeah in North America you only really get to do that if you're near a horse farm with a cool owner.

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Zealousideal-Spend50 t1_j0f0hdo wrote

It wouldn’t be difficult. Go out and collect some mushrooms. Bring them to a lab, dry them out and then do the extraction. As long as that was done quickly and consistently and then the results would be fairly reliable.

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AlbinoWino11 t1_j0f8is1 wrote

You’ve basically described what the authors did. But the other commenter is saying several variables were not suitably controlled for. Which I don’t think is very easy given the hurdles and complications of wild Psilocybe collection from around the world.

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Zealousideal-Spend50 t1_j0fak66 wrote

< You’ve basically described what the authors did.

Not at all. The criticism is that the authors didn’t perform the analysis at a consistent time point after sample collection or account for the different times in their analysis. I described an analytical method that would fix some of those concerns.

> Collecting and possessing wild Psilocybe isn’t very legal for most folks or labs in most places.

I’m not sure how that is relevant. The people involved in the study are already collecting these samples, so either they are licensed to handle controlled substances or don’t care if they are following the law. Either way, they should standardize their sample collection methods or not run the study. If they can’t run the study correctly then they shouldn’t perform the study.

> On top of that these mushrooms don’t just grow everywhere. Or at the same time. And they’d would all probably need to be sent to the same lab.

Somehow, other scientists have been able to run these analytical studies correctly. If it is not feasible for the authors to use the correct procedures then that is a good reason not to attempt the study.

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