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SerialStateLineXer t1_j1zo0xb wrote

Reply to comment by Vito_The_Magnificent in Schooling substantially improves intelligence, but neither lessens nor widens the impacts of socioeconomics and genetics by i_have_thick_loads

>I wonder if you'd get the same results in 18 year olds, or with a more complete PGS model

You'd definitely see genetics play a much larger role. There's a huge amount of missing heritability in PGS models, i.e. they explain only a small portion of the heritability that we know is there from twin studies. As a result, studies like this underestimate the effects of genetics and overestimate the effects of SES.

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FelsensteinsMonster t1_j1zsi73 wrote

This makes a lot of assumptions about estimates from twins being accurate and ignores that the ostensible predictive gains between a 1 million sample education GWAS and a 3 million sample GWAS was mostly lost when confounders were accounted for. If anything the poor quality of polygenic scores will make non-genetic factors appear genetic in these kinds of models

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Vito_The_Magnificent t1_j1zxlzq wrote

>1 million sample education GWAS and a 3 million sample GWAS was mostly lost when confounders were accounted for

Oooo for EA? I didn't see that one. Got the paper handy?

I got stock in 23&Me that I may need to sell if GWAS is gonna cap out at 0.1 on everything.

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