GPT-3 summary:

The breakthrough discussed in this article is a new platform for gene editing that could inform the future application of a near-limitless library of CRISPR-based therapeutics. This breakthrough is significant because it provides a system to deliver the cargo required for generating the gene editing machine known as CRISPR-Cas9. This breakthrough works by transforming the Cas-9 protein into a spherical nucleic acid (SNA) and loading it with critical components as required to access a broad range of tissue and cell types, as well as the intracellular compartments required for gene editing. The article discusses how this breakthrough could help gene editing technology infiltrate cells and overcome a critical limitation of CRISPR.