Progenitor cells and reversing aging

Submitted by Homie4-2-0 t3_yns7nx in singularity

Apparently, progenitor cells are found in most of the tissues in the body and function as tissue-specific stem cells that are in the exact locations they need to be for reprogramming. I've also been reading about how they're trying to use AI to parse out which genes lead to loss of cell identity in epigenetic reprogramming. If they succeed at doing that, it seems like we are tantalizingly close to having cheap and affordable tissue regeneration while also being able to reverse aging in those same tissues. Even if normal stem cells are still necessary for some scenarios, it seems as if we're approaching the holy grail of regenerative medicine extremely fast.

https://longevity.technology/news/the-next-wave-of-regenerative-medicine/

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Dat_Innocent_Guy t1_ivbkl9z wrote

So what are you guys going to do with your new found biological immortality?

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gobbo t1_ivc5ls2 wrote

Probably get around to finally finishing Finnegan's Wake.

Oh, and, learn to dance.

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RavenWolf1 t1_ivd9srt wrote

What I most want is some Matrix like fantasy virtual reality. I know I don't see it happening without biological immortality. So that is my goal. To get some really nice universe for me to play with. While waiting it to happen it is anime, video games and movies. When robots takes our jobs I have even more time to spent to those!

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94746382926 t1_ivd1mm2 wrote

Get really, absurdly good at something without regard for how long it takes. Then after that start probably fuck around for awhile and just do whatever I want (obviously will probably still have to work). Beyond that just normal life stuff like have a family, etc. Once that's done maybe recommit myself to working on extreme moonshot goals that would normally be out of reach during a normal human lifespan. Maybe try and understand how to further improve the intelligence of humans, space travel, etc.

If you're truly immortal though (accidents or violence notwithstanding), then eventually it would probably end in a medical suicide for most people at some point.

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PandaCommando69 t1_ivhjvc4 wrote

Idk about that. In an endless universe there's endless things to do, though I suppose one could get bored. I wonder if God gets bored..

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GhostInTheNight03 t1_ivc6bv7 wrote

Fight the anxiety of what it truly means...it's something I want yes, but it's a bit of a nerve racking thought lol

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freeman_joe t1_ivcenyg wrote

I would use all my time to expand science and learn new skills and would like to explore universe.

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Independent-Book4660 t1_ivcorny wrote

Probably if I were immortal it would be a lot of joy in the more 170 years of life and then each year it would be worse and worse, I could have kids and a dream wife could do a thousand cool things every year but the boredom would always come back.

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ob_frap t1_ivdk8hf wrote

I can finally make my way through all the Ken Burns documentary series

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ihateshadylandlords t1_ivbtle2 wrote

> it seems as if we're approaching the holy grail of regenerative medicine extremely fast.

What is extremely fast in your opinion? I feel like it would take 10 years minimum for this drug to be available for the masses (assuming the FDA approves it and all that other stuff).

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Homie4-2-0 OP t1_ivc3bfd wrote

What constitutes fast for me is if the full suite of regenerative medical technology is in patients' hands by 2050. Some things will happen faster than others, and some drugs are already close to approval, but most, if not all, should be here by 2050. If they aren't, I'm going to be pretty disappointed. Also, phase 2 clinical trials have already started for the drug in the article, so it shouldn't be more than a couple of years.

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