I feel like determining the aa sequence is only the first hurdle. Proteins have meta structures. The sequence is known as the primary structure, there’s secondary, tertiary, quarternary. Which have to do with the way the protein folds around and interacts with itself and others. And they don’t always just fold up nicely into their useful structure, requires chaperone proteins that facilitate that process as well as other proteins they interact with to get it so the free energy is sufficiently low in that local minimum that is the “correct” structure for function.