I'm a neuroscience undergrad and am going into psychedelic research. Psychedelics like Psilocybin open up generalized critical periods of plasticity. These can be used to "rewire" intrusive thoughts or ruminating thoughts. They seem to tap into a mechanism of intrinsic growth that has a goal state leading to a homogeneous energy landscape in the brain. This is all backed up with empirical evidence from research.

https://www.cambridge.org/core/journals/bjpsych-open/article/effects-of-psilocybin-versus-escitalopram-on-rumination-and-thought-suppression-in-depression/2D5B3439C1BC04336534BC229803496F

I'm happy to talk to you about this in more detail.