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Cryptizard t1_j39nw7c wrote

  1. Commercial sequencing mashes together the DNA from thousands of cells, and your recommended "ultra" sequencing reads it 100 times meaning that any individual mutations will be eliminated.

  2. Epigenetics do not change the DNS that is sequenced so have nothing to do with your "save point."

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banuk_sickness_eater OP t1_j39pcjh wrote

1.) The ultra sequencing I've recommended specifically searches for and reports on individual mutations including both coding and non-coding regions.

2.) DNA, as I assume you meant DNA, is the substrate for epigenetic regulation, and changes in the epigenetic marks on DNA can influence the expression of specific genes and have an impact on an individual's traits and susceptibility to certain diseases. Via high-throughput whole genome NGS, the ultra sequence also provides parsable insight into the epigenome.

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