> These NPF-induced changes in food intake were likewise not associated with altered triacylglyceride (TAG) or circulating sugar levels (Extended Data Fig. 1l,m), supporting a direct role for gut-derived NPF in governing feeding behaviour, rather than effects of NPF on metabolism that then lead secondarily to altered behaviour. Together, these results indicate that NPF from these EECs is both necessary and sufficient to inhibit food intake and prevent food overconsumption.
GLP-1 agonists alter insulin patterns and average blood sugar, in addition to appetite suppression and modifying feeding behavior.
Seems like this drug, analogue to NPY in humans, mainly affects feeding behaviors.
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Reply to comment by peoplerproblems in A gut-derived hormone suppresses sugar appetite and regulates food choice in Drosophila (Nov 2022) by basmwklz
> These NPF-induced changes in food intake were likewise not associated with altered triacylglyceride (TAG) or circulating sugar levels (Extended Data Fig. 1l,m), supporting a direct role for gut-derived NPF in governing feeding behaviour, rather than effects of NPF on metabolism that then lead secondarily to altered behaviour. Together, these results indicate that NPF from these EECs is both necessary and sufficient to inhibit food intake and prevent food overconsumption.
GLP-1 agonists alter insulin patterns and average blood sugar, in addition to appetite suppression and modifying feeding behavior.
Seems like this drug, analogue to NPY in humans, mainly affects feeding behaviors.