Aus_scientist
Aus_scientist t1_j4upg4e wrote
Reply to comment by kappusha in How many times mRNA transcript can be translated before it's degraded or something like that? by kappusha
Polysome profiling can give us an indication of translation kinetics. Basically, a transcript can have multiple ribosomes actively translating on it at once - so measuring this. Pairing this info with transcriptomic info you can get the rate of translation. And then knowing the transcript's degradation kinetics can give you an estimate.
Aus_scientist t1_j4uok58 wrote
The primary drivers of the dimorphism between men and women are sex steroid hormones during puberty.
This is a really good review of the topic https://doi.org/10.1016/j.beem.2007.04.007
Just the abstract is sufficient to give a good overview.
Aus_scientist t1_j4upta9 wrote
Reply to comment by being_interesting0 in What determines the lifespan of a species? Why do humans have such a long lifespan compared to say a housecat? by Forking_Shorts92
Similarly, here is a new paper from Sinclair Lab also suggesting this (more specifically loss of epigenetic info). Came out a few days ago and people are still dissecting it.https://www.cell.com/cell/pdf/S0092-8674(22)01570-7.pdf