Unfortunately yes. naproxen is very effective and has a long half life but it is not free from side effects.

This was the initial finding suggesting this in a really small group: McGeer, P. L., et al. (1990). Lancet 335(8696): 1037.

Here is the Rotterdam Study: in t' Veld, B. A., et al. (2001) N Engl J Med 345(21): 1515-1521.

This showed a 5 fold reduction for people who took NSAIDs for more than 2 years. See Table 3 relative risk = 0.2. This caused a lot of excitement.

Alas John Breitner's RCTs say otherwise: ADAPT Research Group. (2008). Arch Neurol 65(7): 896-905.

Meyer, P. F., et al. (2019). Neurology 92(18): e2070-e2080

Maybe, maybe not. NSAID usage over a long period is associated with lower incidence of Alzheimer’s Diesease (Rotterdam study), but two prospective clinical trials ADAPT and INTREPAD were both ended early due to major adverse events. There was no benefit when they were ended at two years. NSAIDS are not harmless even though we get them without a prescription in the US. They raise blood pressure, and can cause bleeding in the gastrointestinal tract as well as kidney damage. A few for a sore knee are likely not going to be a problem, but taking over a long period of time? Use caution. There is no free lunch.