If the standard of care (SoC) and trial drug have different administration routes, then sometimes there can be two placebos involved to mimic either the SoC or the trial drug. E.g. Cohort A will receive SoC pill and a placebo injection, Cohort B will receive a placebo pill and trial drug injection.
Beginning_Swim_4820 t1_ituqh2q wrote
Reply to comment by meontheinternetxx in Can someone explain the ethics of testing potentially life saving medication? by beatleboy07
If the standard of care (SoC) and trial drug have different administration routes, then sometimes there can be two placebos involved to mimic either the SoC or the trial drug. E.g. Cohort A will receive SoC pill and a placebo injection, Cohort B will receive a placebo pill and trial drug injection.