Dabalam t1_jboyzd2 wrote

This is a good example of how causality is not always straightforward.

Serotonin reuptake inhibitors do work and work better the better in people with more severe depression symptoms.

However they generally can only be expected to work after around 2-4 weeks where as the serotonin increase is on day 1.

The mechanism isn't exactly "more serotonin = more happy" but that's a bit complex for most people.


Dabalam t1_j7zsmz1 wrote

I don't think that's accurate. The specific question we're asking is if you control for calories can you achieve the same longevity regardless of diet. Observational studies on people who tend to eat more calorie dense refined food do not control for calorie intake.