Doctor_YOOOU t1_jdw37v7 wrote

>Samples were often described as too small or inadequately created.

This is really interesting to me, and is definitely a communication challenge. There are a lot of reasons why people might perceive a sample as too small - maybe it is! There are a lot of logistical, funding, or statistics reasons why a sample might be the size it is. However, I am not sure those reasons are often communicated for fear of sabotaging one's own conclusions. Without explaining why a sample is the way that it is, it remains open to interpretation and easy criticism.


Doctor_YOOOU OP t1_iy4vujf wrote

Ifosfamide was approved for use in the USA in 1987, but the epigenetic analysis tools used to generate this finding are much newer. In the press release, they don't advocate for stopping use of the drug, but rather to freeze or preserve germ cells so that they are not affected during treatment.