I’m too lazy to look it up, is this applied intravenously and changes all cells it encounters, or just injected directly into the target tissue?

“the technique is still not perfect and can produce some unwanted letter changes; this occurred in Eric Olson’s mice, although apparently without adverse effects.”

I am optimistic these off-target effects can continue to be lowered. Their existence will be a major hurdle going forward.

I think on a certain level everything happens this way. A virus has no neurological system but it is replicated by a series of chemical reactions. If it doesn’t work it doesn’t continue to exist. Same for cell division. When it doesn’t work the cell dies - or becomes cancer and kills the host.

It is hard to conceive of the fact that this system has evolved by these chemicals literally bumping into each other for billions of years.

There are protein complexes which identify the centromeres of the chromosomes to be targeted by the spindle apparatus. The protein complexes bind specifically to the centromeres of the chromosomes. Is this sort of what you were looking for?

I think what foxes was saying is that these interactions are passive, not controlled by a nervous system or anything.