You mean domains? No we are at 3 + 1, with Parakaryon remaining unique and uncharacterised.

People are amazed at how successful my gifts are!

Seems like a good investment.

I was lamenting to Hellenes who may have suffered their wives getting a pang for “gardumba” which is kinda like the Italians call involtini di fraggaglie di agnello — it’s mutton rolled up with offal and liver etc, using intestine as a wrapper and cooked over coals or in an old style baking oven. With potatoes, they love the potatoes.

So imagine she wants that on a Wednesday night and you have to drive out to the coast to the only tavern stupid enough to be open.

Enough to make a man wonder whether having an heir was a good idea.

Άντε τώρα Τετάρτη βράδυ να σου λέει «έχω όρεξη για γαρδούμπα» και να τρέχεις στη Βάρη στα καλά καθούμενα και να αναρωτιέσαι το τον ήθελα τον κληρονόμο.

I suspect non-Med people have a very different idea of what the Med diet actually is though…

In other words, yes. The agency supports vaccination because of the benefits outweighing the risks.

The hypothesis itself isn’t novel though. It seems bipedalism as a better motion modality in arboreal primates evolved several times; for example it seems to have evolved among primates in Europe too.

Conversely, doesn’t exercise activate mTOR-mediated signalling?

It wasn’t bad frankly.

That was late 90s. Beer and spaghetti were both on the McD menu in 1999. Good times.

That’s a relief. I worried it was something I’d said.

Ironically the Med has been experiencing low birth rates since the 1980s.

It seems intuitive certainly.

In those animals, which diet promoted carries?

The problem still remains: it just doesn’t get you high.

Temporal and spatial regulation of gene expression that generates cell lineages comprising interdependent cells with a common genome. Among the metazoans, Porifera have a totipotent and rudimentary stem cell system that still provides mechanisms of development and differentiation. Transdifferentiation remains differentiation and I just see it as the basis of cellular plasticity.

Having dabbled in PDZ domains (before they were named PDZ domains and we just called them discs-large-like domains), I was pleasantly surprised to see recently the discovery of essentially intact post-synaptic density components in a multicellular eukaryote lacking a nervous system — the signalling and scaffolding components were there nonetheless.

Granted, other mechanisms of cell signalling exist that do not rely on animal-style junctions. But the other criteria remain challenging. If we do impose a common genome limitation, which I am convinced is appropriate, then prokaryotes with their relatively widespread propensity toward lateral gene transfer will be even more challenging to accept as anything beyond colonial.

This remains a unicellular prokaryote capable of colonial formations. It may provide indications about a potential evolutionary path toward multicellularity, but I don’t see any data that it has achieved multicellularity.

Filamentous colonies and biofilms are not novel.

This is not a multicellular species.

People also underestimate the prevalence of reposts.

This has been going on for 2 billion years and the existence of gene transfer from mt to nucleus isn’t the point of the article.

Since we’re talking about a process that has lasted billions of years, there’s no particular worry at this point.