Michaelcycle13
Michaelcycle13 t1_j8yu7yq wrote
Reply to comment by discotititis in Scientists find people with Long Covid have 2 major cytokines of the immune system (IL-8, IFN-γ) reduced by 100% by sagdiyev1
Haha we're saying the same thing about the commensal bacteria aspect. I never did say that commensal bacteria activated the T cells as you so put. I'd love to hear more from you. I'm a Long Covid struggler who's on the mend. A lot of people don't know what is going on, medical professionals especially, however, everyone has their theories.
I think through discourse like this we're only going to improve in knowledge and learn more. Obviously I do not have a background in immunology as you say you have. I've also been looking into starting a Long Covid Collaboratory podcast where we bring in other people struggling to share stories, share what helped us, and discuss symptoms. Would you ever be interested in saying some words?
Michaelcycle13 t1_j8ycl9p wrote
Reply to comment by evandegr in Scientists find people with Long Covid have 2 major cytokines of the immune system (IL-8, IFN-γ) reduced by 100% by sagdiyev1
I came across an article the other insinuating that a very possible potential bio marker is the microbiota layout within the gut microbiome.
Michaelcycle13 t1_j8yc5hz wrote
Reply to comment by discotititis in Scientists find people with Long Covid have 2 major cytokines of the immune system (IL-8, IFN-γ) reduced by 100% by sagdiyev1
I see I do appreciate your correction. I’m regurgitating personal at home research from online doctors I’ve watched explaining it and pubmed papers. It looks like I’ve completely messed up the initial signaling from the dendritic cells. I never did say that bacteria or antibodies carried the virus to the thymus to correct you. But that they served a role in signaling to the T cells for response of the immune system. Which is a true scientific statement that I would be happy to share the research on. I was however incorrect about the thymus being the origin of the production of cytokines. I appreciate the correction again. My explanation also was missing the functionality of the dendritic cells, lymph node, and B cell activations for the pathology of immune response. I’d love to ask you more questions because I am fascinated to hear more and to learn more!
Michaelcycle13 t1_j8ya4e5 wrote
Reply to comment by SanaFraley in Scientists find people with Long Covid have 2 major cytokines of the immune system (IL-8, IFN-γ) reduced by 100% by sagdiyev1
I was meaning long Covid. And sorry to hear about these symptoms Man. I’m about to begin a long Covid podcast and we’re aiming at just bringing on people with long Covid for quality collaboration, and discussing our long Covid stories. At the least you make a friend in the community and have some meaningful helpful conversations, at the most you help others through the spread of awareness and knowledge and we blow the lid off this misunderstood illness
Michaelcycle13 t1_j8vms3r wrote
Reply to comment by SanaFraley in Scientists find people with Long Covid have 2 major cytokines of the immune system (IL-8, IFN-γ) reduced by 100% by sagdiyev1
I see. That’s fully understandable. I don’t believe my immune system is performing well either. May I ask, what was your attributed “long Covid” infection like?
Michaelcycle13 t1_j8vm4ds wrote
Reply to comment by FSAaCTUARY in Scientists find people with Long Covid have 2 major cytokines of the immune system (IL-8, IFN-γ) reduced by 100% by sagdiyev1
There is an uncanny correlation between this exact phrase you uttered. It’s based by no scientific basis, some speculative research articles are floating around out there that mention this exact same hypothesis. While I would say it is probable it is not entirely purely 100% accurate. There seems to be a heavier hit to highly cardio active individuals as well.
Michaelcycle13 t1_j8ty619 wrote
Reply to comment by SanaFraley in Scientists find people with Long Covid have 2 major cytokines of the immune system (IL-8, IFN-γ) reduced by 100% by sagdiyev1
That’s good! I believe that it can be misleading to assume that because your thymus appears healthy on a CT scan that your immune system is functioning to par. Be sure you have the vitamin C, D, and Zinc in optimal ranges. There are other residual effects from the virus as well such as gut dysbiosis which is cause a number of continuous downstream effects if gone untreated. I did not mean to say any thymus dysfunction is the explanation for long Covid in it’s entirety. There is malabsorption of vitamins, nutrients, and amino acids; gut permeability, organ inflammation, dysfunction in Short Fatty Chain Acid synthesis, neurotransmitter synthesis, and a likely overgrowth of bad bacteria and yeast.
Michaelcycle13 t1_j8sxvlc wrote
Reply to comment by Rakshear in Scientists find people with Long Covid have 2 major cytokines of the immune system (IL-8, IFN-γ) reduced by 100% by sagdiyev1
GUY BELOW ME KNOWS MORE When a virus invades the host. The body's bacteria along with antibodies find and detect its existence. They then go to deploy Cytokine molecules from the Thymus gland to seek out and kill the viral matter through cells called "T cells", typically called "Killer T Cells". These cells engage the virus and begin to fight it. You usually experience symptoms like Fatigue, Fever, or other bodily dysfunctions during this time as your body is using natural processes to kill viral matter and protect itself.
In the above article it is stating that they are finding people with Long Covid don't have an overreactive immune system. But that they have an underreactive immune system. Specifically lessened Cytokine molecules aka T cells. T cells are the most crucial, when deployed they give the sensations of a "fever" and those other aforementioned bodily dysfunctions.
The Thymus gland produces Cytokine and T Cells. And it is fueled off of Vitamin C and Zinc. Vitamin C and Zinc are shown to be lessened in people with Long COVID. With insufficient nutrition the Thymus gland will have atrophy and shrink. This leading to a understrength baseline Immune System response in the future.
I'm now theorizing that our mild or asymptomatic infections are really red flags that our immune system was underprepared to fight off the virus. Or that our bodies did not have adequate antibodies or [gut] signaling bacteria to detect the existence of the virus for defense or deployment.
Michaelcycle13 t1_j8svy72 wrote
Reply to comment by YourFriendNoo in Scientists find people with Long Covid have 2 major cytokines of the immune system (IL-8, IFN-γ) reduced by 100% by sagdiyev1
Get a micronutrient test done, check your Zinc and Vitamin C levels. They're likely depleted. Zinc and Vitamin C have fundamental roles in nourishing the gland which creates Cytokine molecules (Thymus Gland). Vitamin D also plays a crucial role. If we are insufficient in the nutrition that's responsible for Cytokine function, I would imagine that by bringing the nutrients to healthier levels would lead to higher cytokine levels. Issue is is that prolonged malnutrition of the Thymus gland actually leads it to have atrophy, which will mean lessened fundamental function. The sooner we replenish our Thymus, the better.
Virus's love to deplete Vitamin C and Zinc, because Vitamin C and Zinc are so readily necessary for Cytokine (immune fighting T Cells) to deploy and fight the virus. So not only will the virus deplete these key nutrients, but the key nutrients will be depleted leading to insufficient immune fighting function. Its a loop if you will.
For example, I have had a micronutrient panel done, I have resoundingly low levels of Zinc and Vitamin C. And now looking back realizing that during my last infection, I didn't even have a fever. It was extremely mild. Which is and could be in indication of a under functioning deployment of Killer T Cells to be sent out to fight the virus. As a indication that your T cells are busy fighting the virus is to have a fever, it is the body's natural process for killing viral material. Which makes me think, "Just think how many of us had "mild" or "asymptomatic" infections (no fever). Maybe even from the jab itself. Could our immune system of just been depleted? Hence leading to viral persistence within us still?"
Michaelcycle13 t1_j90k54g wrote
Reply to comment by evandegr in Scientists find people with Long Covid have 2 major cytokines of the immune system (IL-8, IFN-γ) reduced by 100% by sagdiyev1
Yeah, biomesight who is one amongst many investigating this. If given a stool of long Covid in a mix of stool from common people, they could accurately identify who’s is the long Covid one. There are very specific imbalances in the microbiota species