I still don’t fully understand why you’d really care, especially if you’ve moved on, but maybe that’s just me.

Just take this as a hint that she doesn’t want anything more to do with you, get rid of her number and let her live her life.

I don’t understand why you’d want to reach out to an ex at all unless there were children involved or legal issues to sort out. You’re her ex, just leave her alone.

Why might she not reply?

Because you’re an ex, your relationship ended 2 years ago, stop trying to reach out she clearly wants nothing to do with you and to move on with her life, I’d suggest you start trying to do the same.

Some of my closest friends are female due to the fact that I work in a largely female dominated environment, some of my girlfriends closest friends are male due to her having a small but close circle of friends from the small village she grew up in and now working in a largely male dominated environment, I don’t have any issue with her spending with her male friends and she has no issues with me hanging out with my female friends.