aziridine86

aziridine86 t1_j6dpq0u wrote

You need an estimate of when the hydrocodone was taken, and an assumption that it was taken as a single dose. Also need to know the route of administration. Probably oral for hydrocodone. Then google "hydrocodone pharmacokinetics" and compare some graphs. May need to convert units also.

Looks like typical concentrations are around 10-100 ng/mL following normal doses in the 10-60 mg range. A blood concentration of 330 ng/mL is quite high based on very brief research.

Published papers on postmortem concentration in hydrocodone overdose give numbers around 0.4-0.5 mg/L (ug/mL) so overdose sounds plausible here, probably took a dose of >100 mg hydrocodone if I had to guess.

This is not legal or medical advice FYI

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