Saturated fatty acids dampen the immunogenicity of cancer by suppressing STING (Mar 2023) cell.com Submitted by basmwklz t3_122cvmm on March 26, 2023 at 6:04 AM in science 6 comments 19
Loss of fatty acid degradation by astrocytic mitochondria triggers neuroinflammation and neurodegeneration (Mar 2023) nature.com Submitted by basmwklz t3_122cjdt on March 26, 2023 at 5:47 AM in science 8 comments 34
Regional brain glucose metabolism is differentially affected by ketogenic diet: a human semiquantitative positron emission tomography (Mar 2023) link.springer.com Submitted by basmwklz t3_11ip77r on March 5, 2023 at 5:57 AM in science 19 comments 82
Extensive accumulation of misfolded protein aggregates during natural aging and senescence (2023) frontiersin.org Submitted by basmwklz t3_117we9c on February 21, 2023 at 6:18 AM in science 8 comments 23
Pharmacological vitamin C inhibits mTOR signaling and tumor growth by degrading Rictor and inducing HMOX1 expression (Feb 2023) journals.plos.org Submitted by basmwklz t3_116a8x5 on February 19, 2023 at 1:26 PM in science 193 comments 1,535
Low-density lipoprotein balances T cell metabolism and enhances response to anti-PD-1 blockade in a HCT116 spheroid model (2023) frontiersin.org Submitted by basmwklz t3_1161wya on February 19, 2023 at 4:51 AM in science 15 comments 32
Metformin regulates myoblast differentiation through an AMPK-dependent mechanism (Feb 2023) journals.plos.org Submitted by basmwklz t3_11093z4 on February 12, 2023 at 6:33 AM in science 27 comments 125
Cold exposure alters lipid metabolism of skeletal muscle through HIF-1α-induced mitophagy (Feb 2023) bmcbiol.biomedcentral.com Submitted by basmwklz t3_1109232 on February 12, 2023 at 6:30 AM in science 8 comments 49
Effect of long-term caloric restriction on DNA methylation measures of biological aging in healthy adults from the CALERIE trial (Feb 2023) nature.com Submitted by basmwklz t3_10y47vb on February 9, 2023 at 7:48 PM in science 49 comments 189
FMO rewires metabolism to promote longevity through tryptophan and one carbon metabolism in C. elegans (Feb 2023) nature.com Submitted by basmwklz t3_10u6frt on February 5, 2023 at 7:04 AM in science 9 comments 53
The antidiabetic drug metformin aids bacteria in hijacking vitamin B12 from the environment through RcdA (Jan 2023) nature.com Submitted by basmwklz t3_10qna2e on February 1, 2023 at 7:12 AM in science 12 comments 80
The metabolite alpha-ketobutyrate extends lifespan by promoting peroxisomal function in C. elegans (Jan 2023) nature.com Submitted by basmwklz t3_10iiqtg on January 22, 2023 at 12:37 PM in science 20 comments 156
Sodium butyrate activates HMGCS2 to promote ketone body production through SIRT5-mediated desuccinylation (Jan 2023) link.springer.com Submitted by basmwklz t3_1074w89 on January 9, 2023 at 4:43 AM in science 10 comments 30
Brain histone beta-hydroxybutyrylation couples metabolism with gene expression (Jan 2023) link.springer.com Submitted by basmwklz t3_1074u2o on January 9, 2023 at 4:40 AM in science 6 comments 21
Genomics and phenomics of body mass index reveals a complex disease network (Dec 2022) nature.com Submitted by basmwklz t3_1014k76 on January 2, 2023 at 5:37 AM in science 18 comments 259
Sodium fluoride induces skeletal muscle atrophy via changes in mitochondrial and sarcomeric proteomes (Dec 2022) journals.plos.org Submitted by basmwklz t3_zurb8f on December 25, 2022 at 5:18 AM in science No comments 5
Food odor perception promotes systemic lipid utilization (Nov 2022) nature.com Submitted by basmwklz t3_yzyu46 on November 20, 2022 at 8:19 AM in science 8 comments 51
Cold exposure induces dynamic changes in circulating triacylglycerol species, which is dependent on intracellular lipolysis: A randomized cross-over trial (Nov 2022) thelancet.com Submitted by basmwklz t3_yzxhig on November 20, 2022 at 6:52 AM in science 20 comments 220
A modest change in housing temperature alters whole body energy expenditure and adipocyte thermogenic capacity in mice (Nov 2022) journals.physiology.org Submitted by basmwklz t3_ytuysy on November 13, 2022 at 7:37 AM in science 108 comments 938
A gut-derived hormone suppresses sugar appetite and regulates food choice in Drosophila (Nov 2022) nature.com Submitted by basmwklz t3_ytur2l on November 13, 2022 at 7:24 AM in science 22 comments 1,494
Metabolic and physical function are improved with lifelong 15% calorie restriction in aging male mice (Nov 2022) link.springer.com Submitted by basmwklz t3_ynrzl3 on November 6, 2022 at 2:54 PM in science 51 comments 1,035
Low dose lithium supplementation promotes adipose tissue browning and sarco(endo)plasmic reticulum Ca2+ ATPase uncoupling in muscle (Oct 2022) jbc.org Submitted by basmwklz t3_y5dauk on October 16, 2022 at 10:17 AM in science No comments 5
Magnesium Supplementation Stimulates Autophagy to Reduce Lipid Accumulation in Hepatocytes via the AMPK/mTOR Pathway (Oct 2022) link.springer.com Submitted by basmwklz t3_y5d651 on October 16, 2022 at 10:09 AM in science 12 comments 73
Long-term dietary restriction ameliorates ageing-related renal fibrosis in male mice by normalizing mitochondrial functions and autophagy (Oct 2022) link.springer.com Submitted by basmwklz t3_y06fo8 on October 10, 2022 at 5:24 AM in science 7 comments 99
Heavy-load exercise in older adults activates vasculogenesis and has a stronger impact on muscle gene expression than in young adults (Oct 2022) eurapa.biomedcentral.com Submitted by basmwklz t3_xzf0o3 on October 9, 2022 at 7:00 AM in science 78 comments 1,506