becausenope t1_ivgmcmg wrote

I've read that Yersinia pestis, the bacterial pathogen of bubonic plague, does not in fact use the CCR5 receptor for entry.

Would love for someone smarter than I to discuss. Thanks.


becausenope t1_ivda9bm wrote

I think this might fit the bill.

The CCR5 delta 32 mutation creates resistance to HIV-1. It's found in roughly 10% of European and West Asian populations. While we don't know the exact virus to have caused such a mutation to occur, we do know it was selected for a reason, rapidly and much sooner than we had anticipated.