samstown23

samstown23 t1_j5fn20z wrote

You joke but this was a real concern back then. Lots of deaths and serious injuries from getting thrown around in the car in otherwise survivable lower speed impacts.

My parents were rather particular about me wearing a seatbelt, even though that wasn't necessarily the norm at the time. Of course 3yo me wasn't too happy about it but that changed after my dad hit the brakes once and I hit the backrest of the front seat. I actually think he did it deliberately to teach me a lesson and it likely wasn't half as bad as I remember it but that was a time when cars didn't necessarily have seatbelts and people came up with the most ludicrous excuses not to wear them if they did.

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samstown23 t1_ix76y3t wrote

Depends on the strength but assuming 400mg/tablet, it's kind of borderline. While the unsupervised recommended daily dose is a mere 1200mg, higher amounts (up to 3200mg) are possible but require some degree of care (particularly when other drugs are involved, such as MTX, SSRIs, diuretics and others). Body mass should be taken into consideration beyond 2400mg as well.

To cut a long story short, acute toxicity likely isn't the problem but the long term use might be somewhat problematic, if only from the gastrointestinal side. I would definitely consult with a GP on that matter.

On a side note, since you mentioned it, please be careful with paracetamol/acetaminophen (e.g. Tylenol): recommended doses and toxic doses are comparatively close together and a lot of OTC meds (often cold remedies) list it as an ingredient. Accidental overdose is an issue and happens relatively frequently (and I doubt you want a liver transplant). It's not unsafe or bad, quite the contrary, but it is comparatively error-prone.

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