supapoopascoopa

supapoopascoopa t1_jeg1l0i wrote

It is a great idea to spell this out and good advice.

I don’t like at all this idea of “being a burden” on the family as a criterion for withdrawal of life supporting care. I’m an ICU doctor and almost always the family wants the patient kept alive more than the patient does, as the family loves them and doesn’t want to let them go. But the patient is the one who has to suffer the reality of their quality of life. And many will be in nursing facilities so not a “burden” on the decision maker. In addition it is unlikely the decision-maker would use being a burden as their explicit reasoning.

Focus instead on what an acceptable quality of life means to you. Knowing that they are following your wishes is usually what gives people the strength and love to let go.

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supapoopascoopa t1_jcjvu3o wrote

Endogenous retroviruses are defective, only vertically transmitted like other genes, and none yet found are competent to produce virions. But they are all in some sense heritable infections and also “infect” new cells every time a cell divides.

Some can produce proteins and even entire viral like particles using host machinery. These proteins are associated with autoimmune diseases and certain cancers. One could argue these are “active” infections in terms of causing symptoms.

The takehome message as usual is that nature in general and viruses in particular don’t give a hoot about arbitrary definitions.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1187282

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supapoopascoopa t1_j8er07o wrote

There is a lot of water in mechanical ventilation circuits due to condensation from air exhalation from the lungs. In fact many ventilators add humidification to decrease this water loss, which further saturates the circuit.

Warm water will turn into an ecosystem if left undisturbed, especially when exposed to oropharyngeal secretions dripping around an endotracheal tube cuff.

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