The Shawshank Redemption

Red crossing the border and making it to Mexico is his final triumph over institutionalization and his redemption as a human being. The growing realization that Red is the one that gets redeemed, and not Andy, is pretty profound. Andy didn't need redemption. He had faith the entire time. Red needed to be saved, and Andy's faith saved him.

One Flew Over the Cuckoo's Nest

Chief killing McMurphy as a mercy and leaving the institution so he can begin living again is the same story as the above, just with different characters. Can you tell I like redemption stories?

Big Fish

The final realization that his father's stories all held a kernel of truth, and all the myriad characters were real utterly transforms the son in the final scene. He wasn't necessarily a liar, just someone who saw the romanticism of life and brought it out.

Laurie from the Halloween series.

I'm saying this not having seen the recent movie, so maybe she dies at the end of this final chapter. She's clearly a survivor up to that point, though.

No, he's not genetically enhanced.

He's been conditioned, which means he's been physically, emotionally and intellectually manipulated and trained until he's at peak condition, but also completely controllable through a combination of behavioural conditioning and a collection of drugs the Treadstone subjects take daily that make him susceptible to suggestion. He's been turned into the perfect soldier/hit man because he doesn't refuse orders, and just gets the job done, every time. It's worked so well that he doesn't even know his real name or real history. As part of his conditioning, he's been taught to handle pain, control stress, etc. so it can appear like he's superhuman, but he's ... not.

Which leads to your second question ... what's the most scary thing about making these hyper-trained, super controllable, near-automatons? When one of them breaks the conditioning, stops taking the drugs, and learns to think for himself again, realizing that he's been controlled and used as a walking weapon the entire time. Now that HE is choosing his targets, his controllers suspect who his next targets will be .... them!